• 姓名: 肖朝庭
  • 职称: 副教授
  • 学位: 博士
  • 湖南大学
  • 生物学院
教育背景
2007年6月毕业于浙江大学获遗传学博士学位。
工作经历

2007年7月至2009年10月在浙江大学农业部动物病毒学重点实验室、传染病诊治国家重点实验室人兽共患传染病研究室从事禽冠状病毒(IBV)分子流行病学和遗传变异研究。

2009年11月至2011年7月于湖南农业大学动物医学院从事动物传染病的教学和科研工作。

2011年7月至2015年12月赴美国Iowa State University兽医学院从事动物病毒性传染病的博士后研究工作。

2016年1月聘为湖南大学副教授。

学术兼职
是Scientific Reports, Transboundary and Emerging Diseases,DATABASE-OXFORD,Journal of Biotechnology、Infection Genetics and Evolution、J Virol Methods 等国际SCI杂志审稿专家。
教授课程
普通生物学(I)、微生物学
学术成果

已在Journal of Pineal Research(IF2016=10.391、Journal of Virology、Journal of General Virology、Virology、Plos One、Vaccine、Veterinary Research、Veterinary Microbiology、Virus Research、Archives of Virology等国际知名SCI刊源杂志发表论文40余篇,SCI论文总影响因子近120,Google Scholar h指数为19,Google Scholar i10 指數为29,引用近800次。

科研项目
已主持国家自然基金面上项目1 项,目前主持国家重点研发计划项目-畜禽重要疫病病原学与流行病学研究子课题和湖南省自然科学基金各1项。
论文专著

1.Xiao CT, Halbur PG, Opriessnig T. Global molecular genetic analysis of porcine circovirus type 2 (PCV2) sequences confirms presence of four main PCV2 genotypes and reveals a rapid increase of PCV2d. Journal of General Virology, 2015,96(7):1830-41。 IF2014=3.529.

2.Xiao CT, Giménez-Lirola L, Halbur PG, Opriessnig T. Characterization of a novel porcine parvovirus tentatively designated PPV5. PloS One. 2013, 8(6): e65312. doi:10.1371/journal.pone.0065312. IF2013=3.73

3.Xiao CT, Halbur PG, Opriessnig T. Molecular evolutionary genetic analysis of emerging parvoviruses identified in pigs. Infection, Genetics and Evolution, 2013,16:369-376. IF2013=2.768

4.Xiao CT, Giménez-Lirola L, Gerber P, Jiang YH, Halbur P, Opriessnig T. Identification and characterization of novel porcine astroviruses (PAstV) with high prevalence and frequent co-infection of individual pigs with multiple PAstV types. Journal of General Virology. 2013,4(Pt 3):570-582. IF2013=3.127

5.Xiao CT, Gerber PF, Giménez-Lirola LG, Halbur PG, Opriessnig T. Characterization of porcine parvovirus type 2 (PPV2) which is highly prevalent in the USA. Veterinary Microbiology. 2013, 161(3-4):325-330. IF2013=3.127

6.Xiao CT, Halbur PG, Opriessnig T. Complete Genome Sequence of a Newly Identified Porcine Astrovirus Genotype 3 Strain US-MO123. Journal of Virology, 2012, 86(23):13126. IF2013=5.076

7.Xiao CT, Halbur PG, Opriessnig T. Complete genome sequence of a novel porcine circovirus type 2b variant present in cases of vaccine failures in the United States. Journal of Virology. 2012, 86(22):12469. IF2013=5.076

8.Xiao CT, Giménez-Lirola LG, Halbur PG, Opriessnig T.Increasing porcine PARV4 prevalence with pig age in the U.S. pig population. Veterinary Microbiology. 2012, 160(3-4):290-296. IF2013=3.127

9.Xiao CT, Giménez-Lirola L, Huang YW, Meng XJ, Halbur PG, Opriessnig T. The prevalence of Torque teno sus virus (TTSuV) is common and increases with the age of growing pigs in the United States. Journal of Virological Methods. 2012,183(1):40-44, IF2013=1.9

10.Xiao CT, Chu MX, Fu Y, Fang L, Ye SC. Analysis of polymorphism, structure and function of exon 2 of ovine melatonin receptor 1b gene: a clue as to why it lacks expression in sheep. Journal of Pineal Research. 2007, 42(1):97-104. IF2015=9.6。

11.Jiang YH, Xiao CT, Yin SH, Gerber P, Halbur P, Opriessnig T. High prevalence and genetic diversity of porcine bocaviruses (PBoV) in US pigs and identification of multiple novel PBoVs. Journal of General Virology. 2014, 95(Pt 2):453-465. IF2013=3.127

12.Yin SH, Xiao CT, Gerber PF, Beach NM, Meng XJ, Halbur PG, Opriessnig T. Concurrent porcine circovirus type 2a (PCV2a) or PCV2b infection increases the rate of amino acid mutations of porcine reproductive and respiratory syndrome virus (PRRSV) during serial passages in pigs. Virus Research, 2013,178(2):445-451. IF2013=2.745

13.Opriessnig T, Xiao CT, Gerber PF, Halbur PG.Emergence of a novel mutant PCV2b variant associated with clinical PCVAD in two vaccinated pig farms in the U.S. concurrently infected with PPV2. Veterinary Microbiology, 2013, 163(1-2):177-183. IF2013=3.127

14.Giménez-Lirola LG, Xiao CT, Zavala M, Halbur PG, Opriessnig T. Improving ante mortem diagnosis of Erysipelothrix rhusiopathiae infection by use of oral fluids for bacterial, nucleic acid, and antibody detection. Journal of Microbiological Methods. 2013, 92(2):113-121. IF2013=2.161

15.Giménez-Lirola LG, Xiao CT, Halbur PG, Opriessnig T. Development of a novel fluorescent microbead-based immunoassay and comparison with three enzyme-linked immunoassays for detection of anti-Erysipelothrix spp. IgG antibodies in pigs with known and unknown exposure. Journal of Microbiological Methods, 2012, 91(1):73-79. IF2013=2.161

16.Giménez-Lirola LG, Xiao CT, Halbur PG, Opriessnig T. Development and evaluation of an enzyme-linked immunosorbent assay based on a recombinant SpaA protein (rSpaA415) for detection of anti-Erysipelothrix spp. IgG antibodies in pigs. Journal of Microbiological Methods. 2012, 91(1):191-197. IF2013=2.161

17.Chu M, Xiao C, Feng T, Fu Y, Cao G, Fang L, Di R, Tang Q, Huang D, Ma Y, Li K, Li N. Polymorphisms of KiSS-1 and GPR54 genes and their relationships with litter size in sheep. Molecular Biology Reports. 2012,39(3):3291-3297. IF2013=2.506

18.Chu MX, Xiao CT, Fu Y, Fang L, Ye SC. PCR-SSCP Polymorphism of Inhibin βA Gene in Some Sheep Breeds. Asian - Australasian Journal of Animal Sciences. 2007, 20(7) : 1023-1029. IF2013=0.643

19.Thachil A, Gerber PF, Xiao CT, Huang YW, Opriessnig T.Development and application of an ELISA for the detection of porcine deltacoronavirus IgG antibodies.PLoS One. 2015 10(4):e0124363. doi: 10.1371/journal.pone.0124363. eCollection 2015. IF2014=3.534

20.Opriessnig T, Gerber PF, Xiao CT, Halbur PG, Matzinger SR, Meng XJ.Commercial PCV2a-based vaccines are effective in protecting naturally PCV2b-infected finisher pigs against experimental challenge with a 2012 mutant PCV2. Vaccine, 2014, 2(34):4342-4348. IF2013=3.492

21.Xiao CT, Yu XL, Li RC, Zhao D, Li J, Zhang L. Glycoprotein B gene-based phylogenetic analysis of porcine cytomegalovirus isolates. Acta Virologica. 2011, 55(4): 361-363,. IF2013=0.759

22.Xiao CT, Liu ZH, Yu XL, Ge M, Li RC, Xiao BR, Zhou HR. Identification of new defective interfering RNA species associated with porcine reproductive and respiratory syndrome virus infection. Virus Research. 2011, 158(1-2):33-36. IF2013=2.745

23.Xiao CT, Liu R, Song ZY, Liao M, Zhou JY. Genomic characterization of a proventriculitis-associated infectious bronchitis coronavirus. Virus Genes. 2010, 40(3):421-422, IF2013=1.769

24.Xiao CT, Zhang MH, Fu Y, Koh HS. Mitochondrial DNA distinction of northeastern China roe deer, Siberian roe deer, and European roe deer, to clarify the taxonomic status of northeastern China roe deer. Biochemical Genetics. 2007, 45(1-2):93-102. IF2013=0.938

25.Xiao CT, Halbur PG, Opriessnig T. Complete Genome Sequence of a Novel Porcine Parvovirus (PPV) Provisionally Designated PPV5. Genome Announcements. 2013,1(1), e00021-12.

26.Gerber PF, Xiao CT, Chen Q, Zhang J, Halbur PG, Opriessnig T.The spray-drying process is sufficient to inactivate infectious porcine epidemic diarrhea virus in plasma. Veterinary Microbiology, 2014,174 (1-2):86-92. IF2013=3.127.

27.Opriessnig T, Xiao CT, Gerber PF, Zhang J, Halbur PG. Porcine epidemic diarrhea virus RNA present in commercial spray-dried porcine plasma is not infectious to naïve pigs. PLoS One, 2014, 12;9(8):e104766. IF2013=3.73.

28.Opriessnig T, Xiao CT, Gerber PF, Halbur PG. Identification of recently described porcine parvoviruses in archived North American samples from 1996 and association with porcine circovirus associated disease. Veterinary Microbiology, 2014, 173(1-2):9-16. IF2013=3.127.

29.Opriessnig T, Xiao CT, Gerber PF, Halbur PG, Matzinger SR, Meng XJ. The mutant U.S. strain of porcine circovirus type 2 (mPCV2) exhibits similar virulence to the classical PCV2a and PCV2b strains in caesarian-derived colostrum-deprived pigs. Journal of General Virology, 2014,95(Pt 11):2495-503.IF2013=3.127

30.Gerber P, Xiao CT, Cao DJ, Meng XJ, Opriessnig T. Comparison of real-time reverse transcriptase (RT)-PCR assays for detection of swine hepatitis E virus in fecal samples. Journal of Clinical Microbiology, 2014,52:1045-1051. IF2013=4.068

31.Opriessnig T, Gerber PF, Xiao CT, Mogler M, Halbur PG. A commercial vaccine based on PCV2a and an experimental vaccine based on a variant mPCV2b are both effective in protecting pigs against challenge with a 2013 U.S. variant mPCV2b strain. Vaccine. 2014, 32:230-237. IF2013=3.492

32.Liu GH, Li RC, Li J, Huang ZB, Xiao CT, Luo W, Ge M, Jiang DL, Yu XL. Seroprevalence of porcine cytomegalovirus and sapovirus infection in pigs in Hunan province, China. Archives of Virology. 2012, 157(3):521-524. IF2013=2.03

33.Liu GH, Li RC, Huang ZB, Yang J, Xiao CT, Li J, Li MX, Yan YQ, Yu XL. RT-PCR test for detecting porcine sapovirus in weanling piglets in Hunan Province, China. Tropical Animal Health and Production. 2012, 44(7):1335-1339. IF2013=1.09

34.Gerber PF, Johnson J, Shen H, Striegel D, Xiao CT, Halbur PG, Opriessnig T. Association of concurrent porcine circovirus (PCV) 2a and 2b infection with PCV associated disease in vaccinated pigs. Research in Veterinary Science, 2013, 95(2):775-81. IF2013=1.774

35.Xiao CT, Luo Z, Lv SL, Opriessnig T, Li RC, Yu XL. Identification and characterization of multiple porcine astrovirus genotypes in Hunan province, China. Archives of Virology, 2017,162:943-952.

36.Xiao CT, Harmon KM, Halbur PG., Opriessnig T. PCV2d-2 is the predominant type of PCV2 DNA in pig samples collected in the U.S. during 2014–2016. Veterinary Microbiology, 2016, 197:72–77.

37.Opriessnig T, Xiao CT, Halbur PG, Gerber PF, Matzinger SR, Meng XJ. A commercial porcine circovirus (PCV) type 2a-based vaccine reduces PCV2d viremia and shedding and prevents PCV2d transmission to naïve pigs under experimental conditions. Vaccine. 2017, 5(2):248-254.

38.Gerber PF, Xiao CT, Lager K, Crawford K, Kulshreshtha V, Cao D, Meng XJ, Opriessnig T. Increased frequency of porcine epidemic diarrhea virus shedding and lesions in suckling pigs compared to nursery pigs and protective immunity in nursery pigs after homologous re-challenge. Veterinary Research. 2016,47(1):118.

39.Evenson D, Gerber PF, Xiao CT, Halbur PG, Wang C, Tian D, Ni YY, Meng XJ, Opriessnig T. A porcine reproductive and respiratory syndrome virus candidate vaccine based on the synthetic attenuated virus engineering approach is attenuated and effective in protecting against homologous virus challenge. Vaccine. 2016, 34(46):5546-5553.

40.Matzinger SR, Opriessnig T, Xiao CT, Catanzaro N, Beach NM, Slade DE, Nitzel GP, Meng XJ. A chimeric virus created by DNA shuffling of the capsid genes of different subtypes of porcine circovirus type 2 (PCV2) in the backbone of the non-pathogenic PCV1 induces protective immunity against the predominant PCV2b and the emerging PCV2d in pigs. Virology. 2016,498:82-93.

41.Cui J, Fan J, Gerber PF, Biernacka K, Stadejek T, Xiao CT, Opriessnig T. First identification of porcine parvovirus 6 in Poland. Virus Genes. 2017,53:100-104.